No, the Dev team has already done its best to keep the number of clicks to a minimum. Most extra clicks are there for security reasons, to prevent potential exploits. Rest assured that, in time, as the source code for the game is improved, the game will be further streamlined.
Also, some of the clicks you have to do are part of the game engine and will never see a reduction. Some popular examples include mining and combat. Following such careers will involve a monumental amount of clicks, but that is the way they have been designed and that is most likely the way they shall remain for ever.